Extraction of lipids from microalgae using classical and innovative approaches

Jianjun Zhou; Min Wang; Jorge A Saraiva; Ana P Martins; Carlos A Pinto; Miguel A Prieto; Jesus Simal-Gandara; Hui Cao; Jianbo Xiao; Francisco J Barba

doi:10.1016/j.foodchem.2022.132236

Extraction of lipids from microalgae using classical and innovative approaches

Food Chem. 2022 Aug 1:384:132236. doi: 10.1016/j.foodchem.2022.132236. Epub 2022 Jan 29.

Authors

Jianjun Zhou¹, Min Wang², Jorge A Saraiva³, Ana P Martins⁴, Carlos A Pinto⁵, Miguel A Prieto⁶, Jesus Simal-Gandara⁷, Hui Cao⁸, Jianbo Xiao⁹, Francisco J Barba¹⁰

Affiliations

¹ Nutrition and Food Science Area, Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Faculty of Pharmacy, Universitat de València, Avda. Vicent Andrés Estellés, s/n, 46100 Burjassot, València, Spain; Department of Biotechnology, Institute of Agrochemistry and Food Technology-National Research Council (IATA-CSIC), Agustin Escardino 7, 46980 Paterna, Valencia, Spain. Electronic address: jianz@alumni.uv.es.
² Nutrition and Food Science Area, Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Faculty of Pharmacy, Universitat de València, Avda. Vicent Andrés Estellés, s/n, 46100 Burjassot, València, Spain; Department of Biotechnology, Institute of Agrochemistry and Food Technology-National Research Council (IATA-CSIC), Agustin Escardino 7, 46980 Paterna, Valencia, Spain. Electronic address: minwang@alumni.uv.es.
³ LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address: jorgesaraiva@ua.pt.
⁴ LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address: ana.patricia.martins@ua.pt.
⁵ LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address: carlospinto@ua.pt.
⁶ Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Food Science and Technology, Universidade de Vigo - Ourense Campus, E-32004 Ourense, Spain. Electronic address: mprieto@uvigo.es.
⁷ Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Food Science and Technology, Universidade de Vigo - Ourense Campus, E-32004 Ourense, Spain. Electronic address: jsimal@uvigo.es.
⁸ Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Food Science and Technology, Universidade de Vigo - Ourense Campus, E-32004 Ourense, Spain. Electronic address: hui.cao@uvigo.es.
⁹ Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Food Science and Technology, Universidade de Vigo - Ourense Campus, E-32004 Ourense, Spain. Electronic address: jianboxiao@uvigo.es.
¹⁰ Nutrition and Food Science Area, Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Faculty of Pharmacy, Universitat de València, Avda. Vicent Andrés Estellés, s/n, 46100 Burjassot, València, Spain. Electronic address: francisco.barba@uv.es.

PMID: 35240572
DOI: 10.1016/j.foodchem.2022.132236

Abstract

Microalgae, as a photosynthetic autotrophic organism, contain a variety of bioactive compounds, including lipids, proteins, polysaccharides, which have been applied in food, medicine, and fuel industries, among others. Microalgae are considered a good source of marine lipids due to their high content in unsaturated fatty acid (UFA) and can be used as a supplement/replacement for fish-based oil. The high concentration of docosahexaenoic (DHA) and eicosapentaenoic acids (EPA) in microalgae lipids, results in important physiological functions, such as antibacterial, anti-inflammatory, and immune regulation, being also a prerequisite for its development and application. In this paper, a variety of approaches for the extraction of lipids from microalgae were reviewed, including classical and innovative approaches, being the advantages and disadvantages of these methods emphasized. Further, the effects of microalgae lipids as high value bioactive compounds in human health and their use for several applications are dealt with, aiming using green(er) and effective methods to extract lipids from microalgae, as well as develop and extend their application potential.

Keywords: Biological activity; Extraction; Lipids; Microalgae.

MeSH terms

Animals
Dietary Supplements
Eicosapentaenoic Acid / metabolism
Microalgae* / metabolism

Substances

Eicosapentaenoic Acid