Neonatal jaundice in Ghanaian children: Assessing maternal knowledge, attitude, and perceptions

PLoS One. 2022 Mar 3;17(3):e0264694. doi: 10.1371/journal.pone.0264694. eCollection 2022.

Abstract

Background: Neonatal jaundice (NNJ) is a major cause of preventable childhood mortality and long-term impairment especially in countries with significant prevalence of the inherited condition, glucose-6-phosphate dehydrogenase (G6PD) defect. In Ghana, routine screening of pregnant women for G6PD defect is standard care. Prevention of poor health outcomes from NNJ is contingent on population health literacy and early diagnosis. As part of a project to evaluate a screening tool for NNJ, we assessed the knowledge, attitude, and perceptions of Ghanaian mothers on NNJ at baseline.

Methods: Using a cross-sectional design, mothers attending antenatal and postnatal clinics at 3 selected health facilities in 2 geographical regions of Ghana were interviewed. Data on mothers' understanding, perceptions, beliefs, and actions towards NNJ were evaluated. Chi-square test was used to determine the association between selected maternal characteristics and knowledge, attitude, and perception to NNJ.

Results: Of the 504 mothers interviewed, 428(85.4%) had heard about NNJ, 346 (68.7%) said the earliest signs are seen in the eyes, 384(76.2%) knew NNJ may be harmful and 467(92.7%) recommended seeking healthcare for the jaundiced newborn. None of the women knew about G6PD or their G6PD status following antenatal screening. Most did not know the signs/symptoms of severe NNJ. Of the 15 mothers who had had a jaundiced neonate, cost was the most perceived (8 out of 15) barrier to accessing health care. There were significant associations (p-value ≤ 0.05) between maternal age, educational level, and knowledge of NNJ.

Conclusion: Despite the high level of awareness of NNJ, gaps still exit in the knowledge, attitudes and perceptions of mothers concerning NNJ. Improving education of women about the causes, symptoms/signs, and the role of G6PD in severe NNJ is recommended. Addressing barriers to accessing healthcare for the jaundiced infant may enhance timely management of NNJ and reduce the associated complications and mortality.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Child
  • Cross-Sectional Studies
  • Female
  • Ghana / epidemiology
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Infant, Newborn
  • Jaundice, Neonatal* / diagnosis
  • Jaundice, Neonatal* / epidemiology
  • Jaundice, Neonatal* / etiology
  • Mothers
  • Pregnancy

Grants and funding

TL and CEL received funding support for the main study on evaluating a screening tool for neonatal jaundice from the United States Agency for International Development (USAID) through its “Saving Lives at Birth (Round 7)” programme grant (Grant ID: RS 17-08196) but not specifically for this baseline study which was conducted before the evaluation study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.