SARS-CoV-2 pirates the kidneys: A scar(y) story

Jochen Reiser; Ryan Spear; Shengyuan Luo

doi:10.1016/j.cmet.2022.02.005

SARS-CoV-2 pirates the kidneys: A scar(y) story

Cell Metab. 2022 Mar 1;34(3):352-354. doi: 10.1016/j.cmet.2022.02.005.

Authors

Jochen Reiser¹, Ryan Spear², Shengyuan Luo²

Affiliations

¹ Department of Internal Medicine, Rush University, Chicago, IL 60612, USA. Electronic address: jochen_reiser@rush.edu.
² Department of Internal Medicine, Rush University, Chicago, IL 60612, USA.

Abstract

SARS-CoV-2 can cause diverse severe and lasting damage to the kidneys. In the latest issue of Cell Stem Cell, Jansen et al. utilized data gleaned from human kidney autopsies and human induced pluripotent stem cell-derived kidney organoids to investigate the direct effects of SARS-CoV-2 infection on kidney cells. They found that such infections resulted in renal scarring (notably, tubulointerstitial fibrosis).

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

COVID-19*
Cicatrix
Humans
Induced Pluripotent Stem Cells*
Kidney
SARS-CoV-2

Abstract

Publication types

MeSH terms

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