The shortage of medical resources promotes medical treatment reform, and smart healthcare is a promising strategy to solve this problem. With the development of Internet, real-time health status is expected to be monitored at home by using flexible healthcare systems, which puts forward new demands on flexible substrates for sensors. Currently, the flexible substrates are mainly traditional petroleum-based polymers, which are not renewable. As a natural polymer, cellulose, owing to its wide range of sources, convenient processing, biodegradability and so on, is an ideal alternative. In this review, the application progress of nanocellulose in flexible sensors is summarized. The structure and the modification methods of cellulose and nanocellulose are introduced at first, and then the application of nanocellulose flexible sensors in real-time medical monitoring is summarized. Finally, the advantages and future challenges of nanocellulose in the field of flexible sensors are discussed.
医疗资源紧缺推进医疗方式变革，智能医疗正在成为解决医疗资源短缺问题的理想方法。随着互联网的发展，人们期待使用柔性医疗保健系统在居家状态下实现实时健康状态监测，这对传感器所需使用的柔性基材提出了新需求。目前所使用的柔性基材一般是传统的石油基聚合物，不可再生。纤维素作为一种天然聚合物，具有来源广泛，加工方便以及可生物降解等优点，是一种可以替代石油基聚合物的理想材料。本文综述纳米纤维素在柔性传感器中的应用进展，首先介绍纤维素及纳米纤维素的结构及改性方法，然后归纳了纳米纤维素柔性传感器在实时医疗监测中的应用，最后讨论了纳米纤维素在柔性传感器领域的优势及面临的挑战。.
Keywords: Flexible substrates; Nanocellulose; Sensors; Smart healthcare.