An exception to the rule? Regeneration of the injured spinal cord in the spiny mouse

Daniel Wehner; Catherina G Becker

doi:10.1016/j.devcel.2022.02.002

An exception to the rule? Regeneration of the injured spinal cord in the spiny mouse

Dev Cell. 2022 Feb 28;57(4):415-416. doi: 10.1016/j.devcel.2022.02.002.

Authors

Daniel Wehner¹, Catherina G Becker²

Affiliations

¹ Max Planck Institute for the Science of Light, 91058 Erlangen, Germany; Max-Planck-Zentrum für Physik und Medizin, 91058 Erlangen, Germany. Electronic address: daniel.wehner@mpl.mpg.de.
² Center for Regenerative Therapies TU Dresden, Technische Universität Dresden, 01307 Dresden, Germany; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK. Electronic address: catherina.becker@tu-dresden.de.

PMID: 35231422
DOI: 10.1016/j.devcel.2022.02.002

Abstract

The capacity for long-distance axon regeneration and functional recovery after spinal cord injury in the adult has long been thought to be a unique feature of certain non-mammalian vertebrates. However, in this issue of Developmental Cell, Nogueira-Rodrigues et al. report an astonishingly high regenerative ability in the spiny mouse.

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MeSH terms

Animals
Axons*
Disease Models, Animal
Nerve Regeneration
Spinal Cord / physiopathology
Spinal Cord Injuries* / physiopathology
Spinal Cord Injuries* / therapy