COVID-19 and the long-term cardio-respiratory and metabolic health complications

Ruth Ashton; Paul Ansdell; Emily Hume; Tom Maden-Wilkinson; Declan Ryan; Esme Tuttiett; Mark Faghy

doi:10.31083/j.rcm2302053

COVID-19 and the long-term cardio-respiratory and metabolic health complications

Rev Cardiovasc Med. 2022 Feb 9;23(2):53. doi: 10.31083/j.rcm2302053.

Authors

Ruth Ashton¹, Paul Ansdell², Emily Hume², Tom Maden-Wilkinson³, Declan Ryan⁴, Esme Tuttiett⁵, Mark Faghy¹

Affiliations

¹ Human Sciences Research Centre, University of Derby, DE22 1GB Derby, UK.
² Department of Sport, Exercise and Rehabilitation, Northumbria University, NE1 8ST Newcastle upon Tyne, UK.
³ Advanced Well-being Research Centre, Sheffield Hallam University, S9 3TU Sheffield, UK.
⁴ Centre for Physical Activity and Life Sciences, University of Northampton, NN1 5PH Northampton, UK.
⁵ Department of Oncology and Metabolism, The Medical School, University of Sheffield, S19 2RX Sheffield, UK.

PMID: 35229544
DOI: 10.31083/j.rcm2302053

Abstract

Severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) transmission continues to impact people globally. Whilst the acute symptoms and management strategies are well documented, millions of people globally are experiencing a prolonged and debilitating symptom profile that is reported to last months and even years. COVID-19 is a multi-system disease however the magnitude of the effects and its associated legacy is presently not well understood. Early reports indicate that multidisciplinary approaches between clinical and non-clinical entities are needed to provide effective and rehabilitative patient support pathways and restore pre-COVID-19 quality of life and functional status. Accordingly, this review provides a summary of the impact on cardiovascular, inflammatory, respiratory, and musculoskeletal function following an acute COVID-19 infection along with the prolonged effects of long-COVID.

Keywords: COVID-19; cardiometabolic; cardiorespiratory; long-COVID; recovery; rehabilitation.

Publication types

Review

MeSH terms

COVID-19* / complications
Cardiovascular System
Humans
Post-Acute COVID-19 Syndrome
Quality of Life
SARS-CoV-2