Cardiovascular Genetics: The Role of Genetics in Predicting Risk

Med Clin North Am. 2022 Mar;106(2):313-324. doi: 10.1016/j.mcna.2021.11.007. Epub 2022 Feb 2.

Abstract

Many cardiovascular disorders have underlying genetic causes. Clinical genetic testing for cardiovascular disease has become widely available and can be useful for diagnosis, management, and cascade screening in selected conditions and circumstances. This article gives an overview of the current state of genetic testing in inherited cardiovascular conditions, who can benefit from it, and the associated challenges.

Keywords: Cardiovascular genetics; Cascade screening; Genetic counseling; Genetic testing; Inherited cardiovascular disease; Precision medicine.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / diagnosis
  • Cardiovascular Diseases* / genetics
  • Genetic Testing*
  • Humans