Cognitive behavioral therapy for reducing fear of cancer recurrence (FCR) among breast cancer survivors: a systematic review of the literature

BMC Cancer. 2022 Feb 28;22(1):217. doi: 10.1186/s12885-021-08909-y.

Abstract

Background: Fear of cancer recurrence (FCR) has been addressed as a cause of emotional distress among breast cancer survivors (BCSs). This study aimed to systematically review the evidence on randomized controlled trials (RCTs) of cognitive behavioral therapy (CBT) designed to reduce FCR among BCSs.

Methods: A systematic review of published original research articles meeting the inclusion criteria was conducted. Five electronic databases, including the Cochrane Library, CINAHL, PubMed, PsycINFO, and Web of Science, were independently searched to identify relevant articles. The Consolidated Standards of Reporting Trials (CONSORT) 2010 checklist was used to evaluate the quality of the eligible studies.

Results: Through a database search and a manual review process, seventeen quantitative studies with an RCT study design were included in the current systematic review. The interventions varied greatly in length and intensity, but the study designs and methodologies were similar. RCTs with face-to-face interventions of at least 1 month seemed to be more effective in reducing FCR outcomes and complying with than the CONSORT 2010 criteria than those with a brief online or telephone format of interventions; nevertheless, most RCT interventions appeared to be effective.

Conclusions: These findings highlight the importance of conducting well-designed CBT interventions to reduce FCR in BCSs with diverse populations at multiple sites, thereby improving the quality of research in this area.

Keywords: Breast cancer; Cognitive behavioral therapy; Fear of recurrence; Randomized controlled trials.

Publication types

  • Systematic Review

MeSH terms

  • Adult
  • Breast Neoplasms / psychology*
  • Cancer Survivors / psychology*
  • Cognitive Behavioral Therapy*
  • Fear / psychology*
  • Female
  • Humans
  • Middle Aged
  • Neoplasm Recurrence, Local / psychology*
  • Treatment Outcome