Case Report: Persistency Pneumococcal Polysaccharide in Cerebrospinal Fluid During a Post Pneumococcal Chronic Aseptic Meningitis: Coincidental or (Auto-)Inflammatory Embers

Front Pediatr. 2022 Feb 9:10:762457. doi: 10.3389/fped.2022.762457. eCollection 2022.

Abstract

We report the case of a 9-months-old boy that has presented a steroid-dependent post-pneumococcal chronic aseptic meningitis was associated with persistence of pneumococcal cell wall components in cerebrospinal fluid during more than 20 months. Suggesting that this antigenic persistence could be involved in post-infectious manifestations through innate immunity response.

Keywords: aseptic meningitis; chronic aseptic meningitis; innate immunity; pneumococcal cell wall components; pneumococcal meningitis.

Publication types

  • Case Reports