Management of Soft-tissue Tumors With a Size of 2-5 cm, Including Malignancy

Anticancer Res. 2022 Mar;42(3):1555-1562. doi: 10.21873/anticanres.15629.

Abstract

Background/aim: The management of soft-tissue tumors of 2-5 cm is not specified. We investigated the management of these cases.

Patients and methods: Among 105 cases with soft-tissue tumors from 2014 to 2021, 38 with tumors of 2-5 cm were retrospectively reviewed. The clinical characteristics, diagnosis, and management were investigated.

Results: The study population included 14 males and 24 females (mean age=57 years). Common histological diagnoses included lipoma, epidermal cyst, and hemangioma as benign tumors, and leiomyosarcoma (n=2) and metastatic soft-tissue carcinoma (n=1) as malignant tumors. Magnetic resonance imaging, needle and excisional biopsy were performed in 35, 19 and 19 cases, respectively. The mean follow-up period was 7 months. No recurrence was observed.

Conclusion: Malignancy exists, even in soft-tissue tumors of 2-5 cm (3/38; 8%). To avoid unplanned excision, needle biopsy should be considered for cases with magnetic resonance imaging abnormalities.

Keywords: 2-5 cm; MRI; Soft-tissue tumor; malignancy; needle biopsy; unplanned excision.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Needle
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Soft Tissue Neoplasms / diagnostic imaging
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / therapy*
  • Time Factors
  • Treatment Outcome
  • Tumor Burden
  • Unnecessary Procedures
  • Young Adult