The ART of cryopreservation and its changing landscape

Fertil Steril. 2022 Mar;117(3):469-476. doi: 10.1016/j.fertnstert.2022.01.018.

Abstract

The purpose of this review is to educate the reader on the role that cryopreservation has played and continues to play in the ever-evolving field of assisted reproductive technologies, specifically in clinical human fertility treatment. We discuss the science behind the cryopreservation methods and investigated some of the major considerations that any clinic or cryobank faces in terms of risks and liabilities, physical challenges that accompany the constantly growing collection of cryopreserved specimens, and what this means on the ethical and legal front. Finally, we take a glimpse in the future to explore what may be on the horizon for the preservation of gametes and reproductive tissues.

Keywords: Cryopreservation; embryos; gametes; gonadal tissues; vitrification.

Publication types

  • Review

MeSH terms

  • Cryopreservation / methods*
  • Cryopreservation / trends
  • Fertility Preservation / methods*
  • Fertility Preservation / trends
  • Germ Cells / physiology
  • Germ Cells / transplantation
  • Humans
  • Reproductive Techniques, Assisted* / trends
  • Vitrification