Research Progress of Heavy Ion Radiotherapy for Non-Small-Cell Lung Cancer

Int J Mol Sci. 2022 Feb 19;23(4):2316. doi: 10.3390/ijms23042316.

Abstract

Non-small-cell lung cancer (NSCLC) has a high incidence and poses a serious threat to human health. However, the treatment outcomes of concurrent chemoradiotherapy for non-small-cell lung cancer are still unsatisfactory, especially for high grade lesions. As a new cancer treatment, heavy ion radiotherapy has shown promising efficacy and safety in the treatment of non-small-cell lung cancer. This article discusses the clinical progress of heavy ion radiotherapy in the treatment of non-small-cell lung cancer mainly from the different cancer stages, the different doses of heavy ion beams, and the patient's individual factors, and explores the deficiency of heavy ion radiotherapy in the treatment of non-small-cell lung cancer and the directions of future research, in order to provide reference for the wider and better application of heavy ion radiotherapy in the future.

Keywords: carbon ion radiotherapy; curative effect; heavy ion radiotherapy; non-small-cell lung cancer.

Publication types

  • Review

MeSH terms

  • Animals
  • Carcinoma, Non-Small-Cell Lung / radiotherapy*
  • Heavy Ion Radiotherapy / methods
  • Heavy Ions
  • Humans
  • Lung Neoplasms / radiotherapy*
  • Neoplasm Staging / methods