Exopolysaccharides synthesized by lactic acid bacteria: biosynthesis pathway, structure-function relationship, structural modification and applicability

Crit Rev Food Sci Nutr. 2023;63(24):7043-7064. doi: 10.1080/10408398.2022.2043822. Epub 2022 Feb 25.

Abstract

Probiotics and their fermentation products are increasingly been focused on due to their health-boosting effects. Exopolysaccharides (EPS) synthetized by lactic acid bacteria (LAB) are widely applied as texture modifiers in dairy, meat and bakery products owning to their improved properties. Moreover, LAB-derived EPS have been confirmed to possess diverse physiological bioactivities including antioxidant, anti-biofilm, antiviral, immune-regulatory or antitumor. However, the low production and high acquisition cost hinder their development. Even though LAB-derived EPS have been extensively studied for their production-improving, there are only few reports on the systematic elucidation and summary of the relationship among biosynthesis pathway, strain selection, production parameter, structure-function relationship. Therefore, a detailed summary on biosynthesis pathway, production parameter and structure-function relationship of LAB-derived EPS is provided in this review, the structural modifications together with the current and potential applications are also discussed in this paper.

Keywords: Application; biosynthesis; exopolysaccharides; lactic acid bacteria; modification; structure-function relationship.

Publication types

  • Review

MeSH terms

  • Fermentation
  • Lactobacillales* / metabolism
  • Polysaccharides, Bacterial
  • Probiotics*
  • Structure-Activity Relationship

Substances

  • Polysaccharides, Bacterial