Extravascular Dispersion of Polyvinyl Alcohol Microsphere Particles in Uterine Artery Embolization

Biomed Res Int. 2022 Feb 15:2022:7426210. doi: 10.1155/2022/7426210. eCollection 2022.

Abstract

Uterine artery embolization (UAE) is a common minimally invasive treatment of different uterine pathologies, such as fibroids, adenomyosis, and menorrhagia. The procedure involves the injection of embolic agents into the uterine arteries, whereby various particles can be used, such as polyvinyl alcohol (PVA). Complication of UAE is the dispersion of polyvinyl alcohol (PVA) microsphere particles in the uterine body which can lead to a granular vaginal discharge. We report the management of complications of PVA microspheres dispersed from the uterine body causing postprocedural discomfort due to the vaginal passage of microspheres or because of an induced fibroid-size enlargement. The dispersion of the PVA microspheres is one example of a minor UAE complication, which nevertheless causes significant distress to the patient and eventfully requires further surgical interventions.

MeSH terms

  • Adult
  • Extravasation of Diagnostic and Therapeutic Materials*
  • Female
  • Humans
  • Microspheres*
  • Middle Aged
  • Polyvinyl Alcohol / therapeutic use*
  • Retrospective Studies
  • Uterine Artery Embolization / methods*
  • Uterine Diseases / therapy*

Substances

  • Polyvinyl Alcohol