Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review

Medicina (Kaunas). 2022 Jan 26;58(2):184. doi: 10.3390/medicina58020184.

Abstract

Visceral leishmaniasis (also known as kala-azar) is characterized by fever, weight loss, swelling of the spleen and liver, and pancytopenia. If it is not treated, the fatality rate in developing countries can be as high as 100% within 2 years. In a high risk situation for perioperative bleeding due to severe thrombocytopenia/coagulopathy, we present a rare challenge for urgent splenectomy in a patient with previously undiagnosed visceral leishmaniasis. A histologic examination of the spleen revealed a visceral leishmaniasis, and the patient was successfully treated with amphotericin B.

Keywords: impaired hemostasis; splenectomy; thromboelastometry; visceral leishmaniasis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Amphotericin B / therapeutic use
  • Anemia*
  • Fever
  • Humans
  • Leishmaniasis, Visceral* / diagnosis
  • Leishmaniasis, Visceral* / drug therapy
  • Leishmaniasis, Visceral* / epidemiology
  • Splenectomy

Substances

  • Amphotericin B