Current and Emerging Medical Therapies in Pituitary Tumors

J Clin Med. 2022 Feb 12;11(4):955. doi: 10.3390/jcm11040955.

Abstract

Pituitary tumors (PT) represent in, the majority of cases, benign tumors for which surgical treatment still remains, except for prolactin-secreting PT, the first-line therapeutic option. Nonetheless, the role played by medical therapies for the management of such tumors, before or after surgery, has evolved considerably, due in part to the recent development of well-tolerated and highly efficient molecules. In this review, our aim was to present a state-of-the-art of the current medical therapies used in the field of PT and the benefits and caveats for each of them, and further specify their positioning in the therapeutic algorithm of each phenotype. Finally, we discuss the future of PT medical therapies, based on the most recent studies published in this field.

Keywords: acromegaly; cushing’s disease; dopamine agonist; pituitary tumors; prolactinoma; somatostatin.

Publication types

  • Review