Strain Imaging for the Early Detection of Cardiac Remodeling and Dysfunction in Primary Aldosteronism

Yilin Chen; Tingyan Xu; Jianzhong Xu; Limin Zhu; Dian Wang; Yan Li; Jiguang Wang

doi:10.3390/diagnostics12020543

Strain Imaging for the Early Detection of Cardiac Remodeling and Dysfunction in Primary Aldosteronism

Diagnostics (Basel). 2022 Feb 20;12(2):543. doi: 10.3390/diagnostics12020543.

Authors

Yilin Chen^{1

2

3

4

5}, Tingyan Xu^{1

2

3

4

5}, Jianzhong Xu^{1

2

3}, Limin Zhu^{1

2

3}, Dian Wang^{1

2

3}, Yan Li^{1

2

3

4

5}, Jiguang Wang^{1

2

3

4

5}

Affiliations

¹ Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
² State Key Laboratory of Medical Genomics, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
³ Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
⁴ Center for Cardiovascular Evaluations, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
⁵ National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

Abstract

Speckle tracking echocardiography is a novel technique to quantify cardiac function and deformation. It has been applied in a series of cardiovascular diseases for the evaluation of early cardiac impairment. We recently used this technique to investigate cardiac structure and function in patients with primary aldosteronism. Cardiac damage usually occurs earlier in patients with primary aldosteronism than those with primary hypertension, probably because aldosterone hypersecretion is more commonly observed in the former than the latter patients. In this article, we will review the imaging studies, especially with speckle tracking echocardiography, for the detection of early cardiac dysfunction in primary aldosteronism as a disease model.

Keywords: cardiac dysfunction; primary aldosteronism; speckle tracking echocardiography.

Publication types

Review