The predictive value of the ages and stages questionnaire in late infancy for low average cognitive ability at age 5

Acta Paediatr. 2022 Jun;111(6):1194-1200. doi: 10.1111/apa.16309. Epub 2022 Mar 3.

Abstract

Aim: This retrospective, longitudinal study examined the predictive value of the ages and stages questionnaire (ASQ) in late infancy for identifying children who progressed to have low cognitive ability at 5 years of age.

Methods: The ASQ was performed on 755 participants from the Irish BASELINE birth cohort at 24 or 27 months of age. Intelligence quotient was measured at age 5 with the Kaufmann Brief Intelligence Test, Second Edition, and low cognitive ability was defined as a score more than 1 standard deviation below the mean. The ASQ's predictive value was examined, together with other factors associated with low cognitive ability at 5 years.

Results: When the ASQ was performed at 24 or 27 months, the overall sensitivity for identifying low cognitive ability at 5 years was 20.8% and the specificity was 91.1%. Using a total score cut-off point increased the sensitivity to 46.6% and 71.4% at 24 and 27 months, but specificity fell to 74.1% and 67.2%, respectively. After adjusting for ASQ performance, maternal education and family income were strongly associated with cognitive outcomes at 5 years.

Conclusion: The ASQ did not detect the majority of children with low cognitive ability at age 5. Alternative methods need investigation.

Keywords: Kaufman brief intelligence test; ages and stages questionnaire; cognitive ability; early child development; early intervention.

MeSH terms

  • Child
  • Child Development
  • Child, Preschool
  • Cognition*
  • Developmental Disabilities* / diagnosis
  • Humans
  • Infant
  • Longitudinal Studies
  • Retrospective Studies
  • Surveys and Questionnaires