Palladium-Catalyzed Three-Component 1,4-Alkoxyarylation Reaction of [60]Fullerene

Yi-Tan Su; Zheng-Chun Yin; Guan-Wu Wang

doi:10.1021/acs.joc.1c02853

Palladium-Catalyzed Three-Component 1,4-Alkoxyarylation Reaction of [60]Fullerene

J Org Chem. 2022 Mar 18;87(6):4051-4060. doi: 10.1021/acs.joc.1c02853. Epub 2022 Feb 24.

Authors

Yi-Tan Su^{1

2}, Zheng-Chun Yin², Guan-Wu Wang^{2

3}

Affiliations

¹ Department of Medical Imaging, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, P. R. China.
² Hefei National Laboratory for Physical Sciences at Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China.
³ State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.

PMID: 35201777
DOI: 10.1021/acs.joc.1c02853

Abstract

The palladium-catalyzed three-component alkoxyarylation reaction of [60]fullerene with primary/secondary alcohols and aryl iodides generates a series of 1,4-(alkoxy)(aryl)[60]fullerene derivatives. Plausible reaction pathways for the formation of 1,4-(alkoxy)(aryl)[60]fullerenes are proposed. In addition, the electrochemical properties of the synthesized 1,4-alkoxyarylation adducts are investigated.