Successful treatment of tuberculosis verrucosa cutis with fester as primary manifestation with photodynamic therapy and anti-tubercular drugs

Photodiagnosis Photodyn Ther. 2022 Jun:38:102763. doi: 10.1016/j.pdpdt.2022.102763. Epub 2022 Feb 19.

Abstract

Tuberculosis verrucosa cutis (TBVC) is a rare type of cutaneous tuberculosis, which often occurs in the body with good immunity to tuberculosis bacilli. It usually presents as a hyperkeratotic verrucous plaque with polygonal boarders but can mimic or evolved into other dermatosis such as verruca vulgaris, chromoblastomycosis, hyperkeratotic lupus vulgaris, hypertrophic lichen planus, or squamous cell carcinoma, leading to delayed diagnosis. Here, we reported that a 62-year-old patient diagnosed by TBVC with fester as primary manifestation. Photodynamic therapy combined with anti-tuberculosis drugs is an effective method to treat TBVC lesions with fester, and it may shorten the treatment cycle of anti-tuberculosis drugs.

Keywords: Anti-tubercular drugs; Photodynamic therapy; Tuberculosis verrucosa cutis.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Chromoblastomycosis* / drug therapy
  • Humans
  • Lichen Planus* / drug therapy
  • Middle Aged
  • Photochemotherapy* / methods
  • Tuberculosis, Cutaneous* / diagnosis
  • Tuberculosis, Cutaneous* / drug therapy
  • Tuberculosis, Cutaneous* / pathology

Substances

  • Antitubercular Agents