Nanostructured Carbons: Towards Soft-Bioelectronics, Biosensing and Theraputic Applications

Chem Rec. 2022 Jul;22(7):e202100319. doi: 10.1002/tcr.202100319. Epub 2022 Feb 21.

Abstract

Recently, nanostructured carbon-based soft bioelectronics and biosensors have received tremendous attention due to their outstanding physical and chemical properties. The ultrahigh specific surface area, high flexibility, lightweight, high electrical conductivity, and biocompatibility of 1D and 2D nanocarbons, such as carbon nanotubes (CNT) and graphene, are advantageous for bioelectronics applications. These materials improve human life by delivering therapeutic advancements in gene, tumor, chemo, photothermal, immune, radio, and precision therapies. They are also utilized in biosensing platforms, including optical and electrochemical biosensors to detect cholesterol, glucose, pathogenic bacteria (e. g., coronavirus), and avian leucosis virus. This review summarizes the most recent advancements in bioelectronics and biosensors by exploiting the outstanding characteristics of nanocarbon materials. The synthesis and biocompatibility of nanocarbon materials are briefly discussed. In the following sections, applications of graphene and CNTs for different therapies and biosensing are elaborated. Finally, the key challenges and future perspectives of nanocarbon materials for biomedical applications are highlighted.

Keywords: Biosensors; CNTs; Graphene; Nanostructured materials; Soft-bioelectronics; Theraputics.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Graphite* / chemistry
  • Humans
  • Nanostructures* / chemistry
  • Nanotubes, Carbon* / chemistry

Substances

  • Nanotubes, Carbon
  • Graphite