Preparation of Graphene Oxide-loaded Nickel with Excellent Antibacterial Property by Magnetic Field-Assisted Scanning Jet Electrodeposition

Guibin Lou; Ya Chen; Junwei Xu; Yingjuan Qian; Haixia Cheng; Zhen Wei; Youwen Yang; Lida Shen; Cijun Shuai

doi:10.18063/ijb.v8i1.432

Preparation of Graphene Oxide-loaded Nickel with Excellent Antibacterial Property by Magnetic Field-Assisted Scanning Jet Electrodeposition

Int J Bioprint. 2021 Oct 26;8(1):432. doi: 10.18063/ijb.v8i1.432. eCollection 2022.

Authors

Guibin Lou^{1

2}, Ya Chen¹, Junwei Xu¹, Yingjuan Qian³, Haixia Cheng¹, Zhen Wei⁴, Youwen Yang⁵, Lida Shen^{1

2}, Cijun Shuai⁶

Affiliations

¹ College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China.
² Key Laboratory of Digital Medical Equipment Technology of Jiangsu Province, Nanjing 210016, China.
³ MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 China.
⁴ Jiangsu Pharmaceutical Association, Nanjing 210016, China.
⁵ Jiangxi University of Science and Technology, Ganzhou 341000, China.
⁶ State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China.

Abstract

Graphene oxide (GO) is recognized as a promising antibacterial material that is expected to be used to prepare a new generation of high-efficiency antibacterial coatings. The propensity of GO to agglomeration makes it difficult to apply it effectively. A new method of preparing GO-loaded nickel (GNC) with excellent antibacterial property is proposed in this paper. In this work, GNC was prepared on a titanium sheet by magnetic field-assisted scanning jet electrodeposition. The massive introduction of GO on the coating was proven by energy disperse spectroscopy and Raman spectroscopy. The antibacterial performance of GNC was proven by agar plate assessment and cell living/dead staining. The detection of intracellular reactive oxygen species (ROS) and the concentration of nickel ions, indicate that the antibacterial property of GNC are not entirely derived from the nickel ions released by the coating and the intracellular ROS induced by nickel ions, but rather are due to the synergistic effect of nickel ions and GO.

Keywords: Antibacterial coating; Graphene oxide; Jet electrodeposition; Nickel.