F-18 FDG PET/CT in NK/T-Cell Lymphoma that Progressed from Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis

Il-Hyun Kim; Young-Sil An; Su Jin Lee; Joon-Kee Yoon

doi:10.1007/s13139-021-00725-3

F-18 FDG PET/CT in NK/T-Cell Lymphoma that Progressed from Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis

Nucl Med Mol Imaging. 2022 Feb;56(1):59-62. doi: 10.1007/s13139-021-00725-3. Epub 2021 Nov 17.

Authors

Il-Hyun Kim¹, Young-Sil An¹, Su Jin Lee¹, Joon-Kee Yoon¹

Affiliation

¹ Department of Nuclear Medicine & Molecular Imaging, Ajou University School of Medicine, Worldcup-ro 164, Suwon, Kyunggi-do 16499 Republic of Korea.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome involving an uncontrolled immune response with variable triggers. HLH is rare but highly fatal, even with proper treatment; therefore, early recognition and diagnosis are crucial for management. Although the role of F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in HLH is poorly defined, it can provide valuable information on disease status and possible triggers. Herein, we report an F-18 FDG PET/CT study on a case of NK/T-cell lymphoma that progressed from Epstein-Barr virus-associated HLH.

Keywords: Epstein-Barr virus; F-18 FDG PET/CT; Hemophagocytic lymphohistiocytosis; NK/T-cell lymphoma.

Publication types

Case Reports