Medium chain triglycerides (MCT): State-of-the-art on chemistry, synthesis, health benefits and applications in food industry

Compr Rev Food Sci Food Saf. 2022 Mar;21(2):843-867. doi: 10.1111/1541-4337.12926. Epub 2022 Feb 18.

Abstract

Medium chain triglycerides (MCT) are esters of fatty acids with 6 to 12 carbon atom chains. Naturally, they occur in various sources; their composition and bioactivity are source and extraction process-linked. The molecular size of MCT oil permits unique metabolic pathways and energy production rates, making MCT oil a high-value functional food. This review details the common sources of MCT oil, presenting critical information on the various approaches for MCT oil extraction or synthesis. Apart from conventional techniques, non-thermal processing methods that show promising prospects are analyzed. The biological effects of MCT oil are summarized, and the range of need-driven modification approaches are elaborated. A section is devoted to highlighting the recent trends in the application of MCT oil for food, nutraceuticals, and allied applications. While much is debated about the role of MCT oil in human health and wellness, there is limited information on daily requirements, impact on specific population groups, and effects of long-term consumption. Nonetheless, several studies have been conducted and continue to identify the most effective methods for MCT oil extraction, processing, handling, and storage. A knowledge gap exists and future research must focus on technology packages for scalability and sustainability.

Keywords: MCT oil; functional food; health-promoting; ketogenic diet; medium chain triglycerides; nutraceutical.

Publication types

  • Review

MeSH terms

  • Dietary Supplements*
  • Fatty Acids*
  • Food Industry
  • Humans
  • Triglycerides / chemistry

Substances

  • Fatty Acids
  • Triglycerides