Intravenous contrast medium extravasation: systematic review and updated ESUR Contrast Media Safety Committee Guidelines

Eur Radiol. 2022 May;32(5):3056-3066. doi: 10.1007/s00330-021-08433-4. Epub 2022 Feb 17.

Abstract

Need for a review: Guidelines for management and prevention of contrast media extravasation have not been updated recently. In view of emerging research and changing working practices, this review aims to inform update on the current guidelines.

Areas covered: In this paper, we review the literature pertaining to the pathophysiology, diagnosis, risk factors and treatments of contrast media extravasation. A suggested protocol and guidelines are recommended based upon the available literature.

Key points: • Risk of extravasation is dependent on scanning technique and patient risk factors. • Diagnosis is mostly clinical, and outcomes are mostly favourable. • Referral to surgery should be based on clinical severity rather than extravasated volume.

Keywords: Contrast media; Extravasation of diagnostic and therapeutic materials; Prevention and treatments; Risk factors.

Publication types

  • Practice Guideline
  • Systematic Review

MeSH terms

  • Administration, Intravenous
  • Contrast Media* / administration & dosage
  • Contrast Media* / adverse effects
  • Extravasation of Diagnostic and Therapeutic Materials* / prevention & control
  • Humans
  • Risk Factors

Substances

  • Contrast Media