Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in León, Nicaragua

Epidemiol Infect. 2021 Oct 20:149:e247. doi: 10.1017/S0950268821002144.

Abstract

In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.

Keywords: COVID-19; Nicaragua; SARS-CoV-2; epidemiology; seroprevalence.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • COVID-19 / epidemiology*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nicaragua / epidemiology
  • Prevalence
  • SARS-CoV-2 / isolation & purification*
  • Seroepidemiologic Studies
  • Urban Population / statistics & numerical data
  • Young Adult