[Application of proteomics in allergic rhinitis]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Feb;36(2):153-157. doi: 10.13201/j.issn.2096-7993.2022.02.017.
[Article in Chinese]

Abstract

The prevalence of allergic rhinitis(AR)is increasing year by year, which seriously affects the quality of life of patients and causes a heavy burden of social diseases. At present, the diagnosis methods focus on clinical manifestations and allergen detection, but there is no accurate detection method for early diagnosis and prognosis of the disease. With the rapid development of proteomics technology and its wide application in disease research, there is a rapid, sensitive and high-throughput technology platform for the diagnosis and treatment of allergic rhinitis, which provides a platform for the early detection, therapeutic targets and prognosis of the disease. This article reviews the progress of AR in proteomics.

Keywords: biomarkers; proteomics; rhinitis, allergic.

Publication types

  • Review

MeSH terms

  • Allergens
  • Humans
  • Prevalence
  • Proteomics*
  • Quality of Life
  • Rhinitis, Allergic* / diagnosis
  • Rhinitis, Allergic* / therapy

Substances

  • Allergens

Grants and funding

北京市医管中心2018年度第四批青苗计划(No:QML20180702);北京市医管中心科研培育计划(No:PX2017020);北京世纪坛医院院青年基金(No:2019-q12);北京世纪坛医院院内基金(No:2020-C02);北京市医管中心扬帆计划(No:ZYLX201826)