Background: Numb chin syndrome describes sensory neuropathy characterised by numbness in the distribution of the terminal branch of the mandibular division of the trigeminal nerve. This symptom may be overlooked by patients and clinicians due to its mild nature; however, it could represent a serious underlying pathology such as inflammatory conditions or malignancy.
Case presentation: A man in his seventies presented with isolated numbness on the right side of the chin, and no other neurological or constitutional symptoms. Radiology showed a lytic mass in the right side of the mandible protruding through the mental foramen. A multidisciplinary approach revealed the cause of the patient's numb chin syndrome.
Interpretation: This case report illustrates clinical considerations in a patient with numb chin syndrome.