Nonagenarians constitute a fast-growing and high-risk segment of the population, with scarce data on specific outcomes for percutaneous left atrial appendage occlusion (LAAO). The aim of the present paper was to assess the outcomes of nonagenarian patients undergoing LAAO from the prospective global Amplatzer Amulet observational study. Overall, 1088 subjects were prospectively included in the study. Among them, 9 (1%) were nonagenarians. Amulet device implant success was achieved in all patients and the only major procedural adverse event was a pseudoaneurysm. During the 2-year follow-up after LAAO, no ischemic strokes or transient ischemic attacks were reported. Further studies will be necessary to confirm the favorable LAAO outcomes in this growing segment of the atrial fibrillation population.
Keywords: atrial fibrillation; elderly; left atrial appendage occlusion; oral anticoagulation.