Preliminary study on the osseointegration effects of contactless automated implant cavity preparation via femtosecond laser ablation

Shanshan Liang; Jianqiao Zheng; Fusong Yuan

doi:10.1364/BOE.446602

Preliminary study on the osseointegration effects of contactless automated implant cavity preparation via femtosecond laser ablation

Biomed Opt Express. 2021 Dec 3;13(1):82-92. doi: 10.1364/BOE.446602. eCollection 2022 Jan 1.

Authors

Shanshan Liang^{1

2

3

4

5}, Jianqiao Zheng^{1

2

3

4

5}, Fusong Yuan^{1

2

3

4

5}

Affiliations

¹ Center of Digital Dentistry/Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China.
² National Center of Stomatology & National Clinical Research Center for Oral Diseases, Beijing 100081, China.
³ National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing 100081, China.
⁴ Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
⁵ NHC Research Center of Engineering and Technology for Computerized Dentistry, Beijing 100081, China.

Abstract

Microrobots were used to control the femtosecond laser ablation of bone tissues to prepare implant cavities for dental implant surgery. The method was optimized through depth-of-cut experiments of ex vivo rabbit femurs, and the optimized method was used to prepare implant cavities on the left femurs of eight live rabbits. A power of 10 W and a scanning rate of 4000 mm/s were found to be optimal. After seven days of osteoinduction, the expression of collagen type I was significantly higher in the experimental group than in the control group (manually drilled implant cavities). The bone-implant contacts of the experimental group at 4 and 8 weeks were 9.65% and 23.08%, respectively.