Recent advances in polysaccharide-based self-healing hydrogels for biomedical applications

Carbohydr Polym. 2022 May 1:283:119161. doi: 10.1016/j.carbpol.2022.119161. Epub 2022 Jan 25.

Abstract

Hydrogels are a class of polymer materials with three-dimensional networks structure, which can absorb a large number of water and biological fluids. Natural polysaccharides are ideal materials for the preparation of biomimetic hydrogels because of their good biocompatibility and biodegradability. The self-healing hydrogel can achieve healing without external force and prolong the service life of the hydrogel. Therefore, self-healing hydrogels are of great interest in tissue engineering, wound dressings, drug delivery, and tissue engineering. This review aims to introduce the preparation methods, self-healing properties of polysaccharide-based self-healing hydrogels and its potential applications in biomedicine and other fields.

Keywords: Biomedical applications; Hydrogel; Polysaccharide; Self-healing.

Publication types

  • Review

MeSH terms

  • Alginates / chemistry
  • Animals
  • Bandages
  • Biocompatible Materials / chemistry
  • Biocompatible Materials / pharmacology*
  • Biodegradation, Environmental
  • Biomimetics / methods
  • Cell Culture Techniques / methods
  • Cellulose / chemistry
  • Drug Delivery Systems / methods*
  • Humans
  • Hydrogels / chemistry
  • Hydrogels / pharmacology*
  • Hydrogen Bonding
  • Mice
  • Polymers / chemistry
  • Polysaccharides / chemistry
  • Polysaccharides / pharmacology*
  • Tissue Engineering / methods*
  • Water / chemistry
  • Wound Healing / drug effects*

Substances

  • Alginates
  • Biocompatible Materials
  • Hydrogels
  • Polymers
  • Polysaccharides
  • Water
  • Cellulose