Surgical management after Oxaliplatin extravasation: A case report and literature review

J Vasc Access. 2023 Nov;24(6):1239-1243. doi: 10.1177/11297298221075237. Epub 2022 Feb 8.

Abstract

This case report describes a unique case of chronic reaction after extravasation of oxaliplatin. The pain and extensive subcutaneous induration did not resolve after 9 months of conservative treatment. Surgical debridement with removal of the totally implantable venous access device (TIVAD) resulted in immediate resolution of the symptoms. Oxaliplatin has both irritant and vesicant properties that are difficult to distinguish at initial clinical presentation. In most literature cases complaints resolve within 3 months with conservative treatment yet surgical debridement should be considered if complaints persist beyond this period.

Keywords: Totally implantable venous access device; chemotherapy complication; extravasation; oxaliplatin.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Agents* / adverse effects
  • Catheterization, Central Venous* / adverse effects
  • Humans
  • Oxaliplatin / adverse effects

Substances

  • Oxaliplatin
  • Antineoplastic Agents