Objective: To evaluate the efficacy of serum uric acid on inpatient morbidity and mortality among acute coronary syndrome patients.
Methods: The hospital-based study was conducted in the Coronary Care Unit of Al-Yarmouk Teaching Hospital, Baghdad, Iraq, from June 1, 2019, to February 28, 2020, and comprised acute coronary syndrome patients of either gender aged >18 years. Other than the demographics, data was collected on echocardiography findings, cardiac markers and serum uric acid level. Data was analysed using SPSS 20.
Results: Of the 70 patients, 49(70%) were male and 21(30%) were female. Overall, 44(62.8%) patients had normal uric acid level and 26(37.2%) had hyperuricaemia. Mean serum uric acid concentration was 5.6±1.6mg/dl (range: 2.5-9.3mg/dl). There was a significant association between patients presenting with heart failure and hyperuricaemia (p<0.05). Complications, such as arrhythmia and heart failure, occurred more in patients with hyperuricaemia (p<0.05).
Conclusions: There was an association between hyperuricaemia and in-hospital complications of patients with acute coronary syndrome in comparison with patients with normal serum uric acid levels.
Keywords: Acute coronary syndrome, Heart failure, Hyperuricaemia, Arrhythmia..