Bioactivities, Applications, Safety, and Health Benefits of Bioactive Peptides From Food and By-Products: A Review

Ahmed A Zaky; Jesus Simal-Gandara; Jong-Bang Eun; Jae-Han Shim; A M Abd El-Aty

doi:10.3389/fnut.2021.815640

Bioactivities, Applications, Safety, and Health Benefits of Bioactive Peptides From Food and By-Products: A Review

Front Nutr. 2022 Jan 20:8:815640. doi: 10.3389/fnut.2021.815640. eCollection 2021.

Authors

Ahmed A Zaky¹, Jesus Simal-Gandara², Jong-Bang Eun³, Jae-Han Shim⁴, A M Abd El-Aty^{5

6}

Affiliations

¹ National Research Centre, Department of Food Technology, Food Industries and Nutrition Research Institute, Cairo, Egypt.
² Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, Universidade de Vigo, Ourense, Spain.
³ Department of Food Science and Technology, Chonnam National University, Gwangju, South Korea.
⁴ Natural Products Chemistry Laboratory, Biotechnology Research Institute, Chonnam National University, Gwangju, South Korea.
⁵ Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
⁶ Department of Medical Pharmacology, Medical Faculty, Ataturk University, Erzurum, Turkey.

Abstract

Bioactive peptides generated from food proteins have great potential as functional foods and nutraceuticals. Bioactive peptides possess several significant functions, such as antioxidative, anti-inflammatory, anticancer, antimicrobial, immunomodulatory, and antihypertensive effects in the living body. In recent years, numerous reports have been published describing bioactive peptides/hydrolysates produced from various food sources. Herein, we reviewed the bioactive peptides or protein hydrolysates found in the plant, animal, marine, and dairy products, as well as their by-products. This review also emphasizes the health benefits, bioactivities, and utilization of active peptides obtained from the mentioned sources. Their possible application in functional product development, feed, wound healing, pharmaceutical and cosmetic industries, and their use as food additives have all been investigated alongside considerations on their safety.

Keywords: applications; bioactive peptides; bioactivities; health benefits; safety.

Publication types

Review