Absence of transmission of NDM and OXA-48 carbapenemase genes in a chronic care unit of a long-term care facility

Carl Boodman; Natalie Gibson; Davenna Conrod; Christine Y Turenne; David C Alexander; Tatyana Taubes; Ana Lucha; David A Boyd; Laura F Mataseje; Michael Mulvey; James A Karlowsky; Molly Blake; John M Embil

doi:10.1177/17571774211012443

Absence of transmission of NDM and OXA-48 carbapenemase genes in a chronic care unit of a long-term care facility

J Infect Prev. 2022 Jan;23(1):15-19. doi: 10.1177/17571774211012443. Epub 2021 Jun 22.

Authors

Carl Boodman^{1

2}, Natalie Gibson³, Davenna Conrod³, Christine Y Turenne^{2

4}, David C Alexander^{2

5}, Tatyana Taubes⁶, Ana Lucha⁶, David A Boyd⁷, Laura F Mataseje⁷, Michael Mulvey^{2

7}, James A Karlowsky^{2

4}, Molly Blake³, John M Embil^{1

2

3}

Affiliations

¹ Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.
² Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada.
³ Infection Prevention and Control Program, Winnipeg Regional Health Authority, Winnipeg, Canada.
⁴ Shared Health, Winnipeg, Canada.
⁵ Cadham Provincial Laboratory, Winnipeg, Canada.
⁶ Deerlodge Centre, Winnipeg, Canada.
⁷ National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.

Abstract

Infection prevention and control measures are used to contain outbreaks of carbapenemase-producing Enterobacteriaceae. We report the absence of transmission of Klebsiella pneumoniae carrying New Delhi metallo-β-lactamase and oxacillinase-48 genes among 19 screened contacts of an index case after 14 months of routine practices in a long-term care facility.

Keywords: New Delhi metallo-β-lactamase (NDM); carbapenemase; chronic care; long-term care; oxacillinase (OXA)-48.