Central Retinal Vein Occlusion in a Young Healthy COVID-19 Patient: A Case Report and Literature Review

Middle East Afr J Ophthalmol. 2021 Dec 31;28(3):199-202. doi: 10.4103/meajo.meajo_271_21. eCollection 2021 Jul-Sep.

Abstract

Coronavirus disease (COVID-19) has been declared by the World Health Organization as a pandemic on March 11, 2020. COVID-19 predispose patients to multisystem thromboembolic events, including pulmonary emboli and deep vein thrombosis. We report a 33-year-old previously healthy man, with previous history of COVID-19 infection presented with left eye central retinal vein occlusion (CRVO) with secondary macular edema. All possible risk factors for thromboembolic events were excluded. After a single dose of intravitreal injection of aflibercept (2 mg in 0.05 ml), gradual improvement in the clinical manifestation of CRVO with complete resolution of macular edema in the left eye was observed. To the best of our knowledge, this is the first report of CRVO post-COVID-19 in Oman.

Keywords: Central retinal vein occlusion; intravitreal injection; macular edema; severe acute respiratory syndrome-CoV-2 infection (COVID-19).

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Angiogenesis Inhibitors / therapeutic use
  • COVID-19*
  • Humans
  • Intravitreal Injections
  • Macular Edema* / diagnosis
  • Macular Edema* / drug therapy
  • Macular Edema* / etiology
  • Male
  • Retinal Vein Occlusion* / diagnosis
  • Retinal Vein Occlusion* / drug therapy
  • SARS-CoV-2
  • Treatment Outcome
  • Visual Acuity

Substances

  • Angiogenesis Inhibitors