The effect of insight, loneliness, and hope levels on medication adherence in patients with schizophrenia

Perspect Psychiatr Care. 2022 Oct;58(4):2208-2214. doi: 10.1111/ppc.13048. Epub 2022 Feb 5.

Abstract

Purpose: It is important to investigate the negative factors affecting medication compliance to continue the treatment of schizophrenia.

Design and methods: In this descriptive and analytical study, the effects of insight, loneliness, and hope levels on medication adherence in 202 patients with schizophrenia were studied.

Findings: The correlation was positive between medication adherence and insight, negative between medication adherence and loneliness, and no correlation between medication adherence and hope. A 1-point increase in insight scores increased medication adherence 1.226 times and a 1-point increase in loneliness scores decreased medication adherence 0.946 times. Medication adherence was 0.499 times lower in nonsmokers compared to smokers.

Practice implications: Further studies on patients with schizophrenia should be conducted to evaluate factors affecting medication adherence and preventing smoking in schizophrenia.

Keywords: hope; insight; loneliness; medication adherence; schizophrenia.

MeSH terms

  • Antipsychotic Agents* / therapeutic use
  • Humans
  • Loneliness
  • Medication Adherence
  • Schizophrenia* / drug therapy

Substances

  • Antipsychotic Agents