Vasodilator therapy

Am J Med. 1986 Feb 28;80(2B):54-8. doi: 10.1016/0002-9343(86)90146-4.

Abstract

Vasodilators are a group of drugs with various degrees of arteriolar or venous dilatation used in the treatment of congestive heart failure when symptoms persist after digoxin and diuretic therapy. Nitrates and captopril provide the most consistent improvement in symptoms. Reduced mortality rates in congestive heart failure with vasodilator therapy has not been demonstrated, and prediction of clinical response to therapy is difficult.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Captopril / administration & dosage
  • Cardiac Output / drug effects
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Heart Failure / drug therapy*
  • Hemodynamics / drug effects
  • Humans
  • Hydralazine / administration & dosage
  • Nitrates / administration & dosage
  • Physical Exertion / drug effects
  • Prazosin / administration & dosage
  • Random Allocation
  • Stroke Volume / drug effects
  • Time Factors
  • Vasodilator Agents / administration & dosage
  • Vasodilator Agents / therapeutic use*

Substances

  • Nitrates
  • Vasodilator Agents
  • Hydralazine
  • Captopril
  • Prazosin