Transcultural adaptation and validation of the Serbian version of the colorectal-specific quality of life questionnaire FACT-C

Jelena Ilic-Zivojinovic; Igor Krdzic; Ana Jovanovic; Danka Vukasinovic; Branislav Ilic; Aleksandar Gavrilovic; Ivan Soldatovic

doi:10.1371/journal.pone.0263110

Transcultural adaptation and validation of the Serbian version of the colorectal-specific quality of life questionnaire FACT-C

PLoS One. 2022 Feb 3;17(2):e0263110. doi: 10.1371/journal.pone.0263110. eCollection 2022.

Authors

Jelena Ilic-Zivojinovic¹, Igor Krdzic², Ana Jovanovic¹, Danka Vukasinovic¹, Branislav Ilic³, Aleksandar Gavrilovic^{4

5}, Ivan Soldatovic⁶

Affiliations

¹ Faculty of Medicine, Institute of Hygiene and Medical Ecology, University of Belgrade, Belgrade, Serbia.
² Department of Colorectal Surgery, University Clinical Hospital Center Zvezdara, Surgery Clinic "Nikola Spasić", Belgrade, Serbia.
³ School of Dental Medicine, Clinic for Oral Surgery, University of Belgrade, Belgrade, Serbia.
⁴ Department of Neurology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
⁵ Clinic of Neurology, University Clinical Center Kragujevac, Kragujevac, Serbia.
⁶ Faculty of Medicine, Institute of Medical Statistics and Informatic, University of Belgrade, Belgrade, Serbia.

Abstract

Objective: Transcultural adaptation and validation of the FACT-C questionnaire to Serbian language.

Methods: The study included 131 patients with colorectal cancer. Translation included standard forward and backward translation from original language to Serbian and back. Pilot testing of the questionnaire was conducted on 10 patients with diagnosed colorectal cancer. The questionnaires EORTC-QLQ-C30 and DASS will be used as validated tools to evaluate validity of examined, FACT-C questionnaire.

Results: The FACT-C demonstrated satisfactory construct validity using Cronbach's alpha. Satisfactory concurrent validity was demonstrated using correlations with EORTC-QLQ-C30 and DASS questionnaires. High reproducibility was demonstrated using repeated questionnaires on 30 patients two weeks after the first interview.

Conclusion: The Serbian version of the FACT-C was demonstrated to have satisfactory applicability, reliability and validity in Serbian patients with colorectal cancer. It can be considered as a valid colorectal cancer specific health related quality of life tool for the Serbian population.

MeSH terms

Adaptation, Physiological*
Aged
Colorectal Neoplasms / psychology*
Colorectal Neoplasms / therapy
Combined Modality Therapy
Cultural Characteristics*
Female
Humans
Language*
Male
Quality of Life*
Reproducibility of Results
Surveys and Questionnaires
Translations

Grants and funding

The author(s) received no specific funding for this work.