Clinical Characteristics and Death Risk Factors of Severe Sepsis in Children

Comput Math Methods Med. 2022 Jan 24:2022:4200605. doi: 10.1155/2022/4200605. eCollection 2022.

Abstract

Sepsis is a systemic inflammatory response syndrome caused by viral infection. The circulatory dysfunction caused by sepsis is also called septic shock or septic shock. The main characteristics are rapid onset, rapid changes, and involvement. Multiple organs in the body make diagnosis difficult, which seriously threatens the survival of patients. As many as one million people worldwide die every year because of SIRS, it is also the leading cause of death among children in hospital ICUs. This article is aimed at studying the clinical characteristics of severe sepsis in children and the risk factors for death. Based on the analysis of the pathogenesis of sepsis and the treatment of septic shock, 65 cases of children with PICU sepsis admitted to a hospital were selected. Data, to study its clinical characteristics and risk factors for death. The results of the study showed that despite the interaction among the removal factors of the three indexes of serum lactic acid value, PCIS level, and the number of organs involved in MODS, they are still related to the mortality of children with severe sepsis.

Publication types

  • Retracted Publication

MeSH terms

  • Apoptosis
  • Bacterial Infections / complications
  • Child
  • Child, Preschool
  • China / epidemiology
  • Computational Biology
  • Cytokines / biosynthesis
  • Disseminated Intravascular Coagulation / complications
  • Female
  • Humans
  • Immunity, Innate
  • Infant
  • Intensive Care Units, Pediatric
  • Male
  • Multiple Organ Failure / diagnosis
  • Multiple Organ Failure / etiology
  • Multiple Organ Failure / mortality
  • Retrospective Studies
  • Risk Factors
  • Sepsis / diagnosis*
  • Sepsis / etiology
  • Sepsis / mortality*
  • Shock, Septic / etiology
  • Shock, Septic / mortality
  • Shock, Septic / therapy

Substances

  • Cytokines