Can recombinant milk proteins replace those produced by animals?

Curr Opin Biotechnol. 2022 Jun:75:102690. doi: 10.1016/j.copbio.2022.102690. Epub 2022 Jan 31.

Abstract

The consumption of animal proteins in general, and dairy proteins in particular, is associated with sustainability and animal welfare issues. Recombinant synthesis of milk proteins is therefore receiving increasing interest, with several studies showing synthesis of milk proteins using a wide range of expression systems. Achieving a high yield and purity is essential for economic production. Besides the synthesis, also the construction of the specific structure in which milk proteins are present in animal milks, casein micelles, is needed. Looking at the current state-of-the-art, the steps to produce recombinant dairy products are technically feasible, but whether it can be implemented at low cost, with the process being environmentally friendly, remains to be seen in the coming years.

Publication types

  • Review

MeSH terms

  • Animals
  • Milk Proteins* / analysis
  • Milk Proteins* / metabolism
  • Milk* / chemistry
  • Milk* / metabolism
  • Recombinant Proteins / metabolism

Substances

  • Milk Proteins
  • Recombinant Proteins