We demonstrate that the multipoles associated with the density matrix are truly observable quantities that can be unambiguously determined from intensity moments. Given their correct transformation properties, these multipoles are the natural variables to deal with a number of problems in the quantum domain. In the case of polarization, the moments are measured after the light has passed through two quarter-wave plates, one half-wave plate, and a polarizing beam splitter for specific values of the angles of the wave plates. For more general two-mode problems, equivalent measurements can be performed.