Seroepidemiology of leptospirosis in livestock and workers of high-risk occupation in Kurdistan, Iran

Shadi Aghamohammad; Arian Hajijafari Anaraki; Maryam Rahravani; Mojtaba Rastin; Reza Atashin Sadaf; Meysam Moravedji; Mahdi Rohani

doi:10.1016/j.cimid.2022.101758

Seroepidemiology of leptospirosis in livestock and workers of high-risk occupation in Kurdistan, Iran

Comp Immunol Microbiol Infect Dis. 2022 Jan 31:82:101758. doi: 10.1016/j.cimid.2022.101758. Online ahead of print.

Authors

Shadi Aghamohammad¹, Arian Hajijafari Anaraki², Maryam Rahravani², Mojtaba Rastin², Reza Atashin Sadaf², Meysam Moravedji³, Mahdi Rohani⁴

Affiliations

¹ Department of Microbiology, Pasteur Institute of Iran, Tehran, Iran.
² Faculty of Veterinary Medicine, Kurdistan Unit of Azad University, Kurdistan, Iran.
³ Faculty of Veterinary Medicine, Kurdistan Unit of Azad University, Kurdistan, Iran. Electronic address: moravedji@iausdj.ac.ir.
⁴ Department of Microbiology, Pasteur Institute of Iran, Tehran, Iran. Electronic address: kia.rohani@gmail.com.

PMID: 35101844
DOI: 10.1016/j.cimid.2022.101758

Abstract

Background: Leptospirosis is one of the major zoonotic infectious diseases which could cause disease in both animals and humans. Using ELISA is one of the serological tests that could be used in the detection of leptospirosis. Based on the different reports about the prevalence of leptospirosis in different parts of our country, we aimed to investigate the rate of Leptospira spp, among livestock and human in Kurdistan province.

Material and method: ELISA assay was performed by ELISA kit (Novatec, Germany) for quantitative detection of anti-Leptospira IgG in human and IgM antibody and total antibodies (IgM and IgG) in serum samples of livestock.

Results: In the present study, the seroprevalence in sheep, goats, and cows was (2/30) 6.7% [95% CI 0.8%,22.1%], (1/31) 3.2% [ 95% CI 0.08%,16.7%] and 0%, respectively. Also, the rate of anti-Leptospira was (1/51) 1.9% [95% CI 0.05%,10.4%] among 51 human participants.

Discussion: the current study, provided some valuable information on the rate of leptospirosis in animal and human participants from west of Iran, which can be useful in terms of monitoring the disease in the area and helping the health care system to control the roots of bacterial transmission.

Keywords: Leptospirosis; Livestock; Seroepidemiology.