Brain on fire: an imaging-based review of autoimmune encephalitis

Clin Imaging. 2022 Apr:84:1-30. doi: 10.1016/j.clinimag.2021.12.011. Epub 2021 Dec 31.

Abstract

Autoimmune encephalitis represents an increasingly recognized group of immune-mediated disorders the affect the central nervous system. The purpose of this article is to highlight the characteristic MR imaging findings associated with autoimmune encephalitis, describe the pathophysiology, review antibodies that have been identified and their patterns of CNS involvement, and discuss approaches to management. Familiarity with the imaging and clinical features of autoimmune encephalitis will prompt the radiologist to suggest the diagnosis which can facilitate appropriate management.

Keywords: Autoimmune encephalitis; Central nervous system; Limbic encephalitis; MRI.

Publication types

  • Review

MeSH terms

  • Brain / diagnostic imaging
  • Central Nervous System
  • Encephalitis* / diagnostic imaging
  • Hashimoto Disease* / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging