Current Status and Emerging Options for Automated Insulin Delivery Systems

Diabetes Technol Ther. 2022 May;24(5):362-371. doi: 10.1089/dia.2021.0514. Epub 2022 Mar 14.

Abstract

Combining technologies including rapid insulin analogs, insulin pumps, continuous glucose monitors, and control algorithms has allowed for the creation of automated insulin delivery (AID) systems. These systems have proven to be the most effective technology for optimizing metabolic control and could hold the key to broadly achieving goal-level glycemic control for people with type 1 diabetes. The use of AID has exploded in the past several years with several options available in the United States and even more in Europe. In this article, we review the largest studies involving these AID systems, and then examine future directions for AID with an emphasis on usability.

Keywords: Artificial pancreas; Automated insulin delivery; Hybrid closed loop; Type 1 diabetes.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Blood Glucose
  • Diabetes Mellitus, Type 1* / drug therapy
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Insulin Infusion Systems
  • Pancreas, Artificial*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin