Construction of coral rod-like MoS2@HA nanowires hybrids for highly effective green antisepsis

J Inorg Biochem. 2022 Apr:229:111724. doi: 10.1016/j.jinorgbio.2022.111724. Epub 2022 Jan 12.

Abstract

Antibacterial materials have been rapidly emerging as a primary component in the mitigation of bacterial pathogens, and green functional materials play a vital role in the antibacterial field. In this study, biocompatible hydroxyapatite nanowires (HANW) was used as a carrier, a coral rod-like nanowires hybrid of MoS2 and HANW (CR-MoS2@HANW) was synthesized via a facile two-step hydrothermal approach. After being characterized by scanning electron microscope (SEM), energy dispersive spectrometer (EDS), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), fourier transform infrared spectroscopy (FT-IR), Brunauer-Emmet-Teller (BET) and thermogravimetric (TG) analysis, the antibacterial activity and environmental compatibility were assessed. It was found that MoS2 nanosheets were in-situ assembled onto surface of HA nanowires, and the obtained nanohybrid exhibited excellent stability. CR-MoS2@HANW endowed a desirable long-term antibacterial activity against both gram-negative E. coli and gram-positive S. aureus. It was sufficient to inhibit the growth of bacteria within 72 h, and nanohybrids effectively promoted the growth of plants. In summary, the combination of MoS2 and HANW created a novel eco-friendly nanohybrids that could be applied as a promising multi-functional green antisepsis. And the CR-MoS2@HANW possessed enormous potential for biomedical applications.

Keywords: Antibacterial activity; Eco-friendly materials; Hydroxyapatite nanowires; Molybdenum disulfide; Nanohybrids; Stability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Infective Agents, Local / chemical synthesis
  • Anti-Infective Agents, Local / pharmacology*
  • Disulfides / chemical synthesis
  • Disulfides / pharmacology*
  • Durapatite / chemical synthesis
  • Durapatite / pharmacology*
  • Escherichia coli / drug effects
  • Green Chemistry Technology
  • Microbial Sensitivity Tests
  • Molybdenum / pharmacology*
  • Nanowires / chemistry*
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents, Local
  • Disulfides
  • Molybdenum
  • Durapatite
  • molybdenum disulfide