[From an optimal management of bone tissue samples to a quality patients' care in 2022 : A new paradigm]

Abstract

Bone tissue can be involved by primitive or metastatic tumors and requires a specific processing both at the department of pathology and during multidisciplinary meetings. The development of fine-needle percutaneous biopsies and of molecular techniques in bone tumor pathology requires a specific management. Moreover, decalcification of samples is crucial but can be deleterious if not controlled or not appropriate. The aim of this review is to provide recommendations for management and decalcification of bone tumor samples.

Keywords: Biologie moléculaire; Bone pathology; Decalcification; Décalcification; Immunohistochemistry; Immunohistochimie; Molecular biology; Pathologie osseuse; Pre-analytical; Pré-analytique.