[Notochordal tumors: From notochord to chordoma]

Abstract

The group of notochordal tumors consists of the benign notochordal cell tumor and the conventional, dedifferentiated and poorly differentiated chordomas in the fifth edition of the WHO classification of bone and soft tissue tumors. This update covers recent advances in the knowledge of the histogenesis and biology of these tumors and their implications in terms of diagnosis, prognosis assessment and therapeutic management.

Keywords: Chordoma; Chordome; Notochord; Notochordal tumor; Notochorde; Tumeur notochordale.