Modeling of COVID-19 disease disparity in gastric organoids reveals the spatiotemporal dynamics of SARS-CoV-2 infectivity
J Mol Cell Biol
.
2022 May 20;14(2):mjac007.
doi: 10.1093/jmcb/mjac007.
Authors
Wenwen Wang
1
2
,
Fengrui Yang
1
2
3
,
Jie Lin
4
,
Saravanakumar Muthusamy
2
,
Shihao Du
1
4
,
McKay Mullen
1
2
,
Fatima Garba
2
,
Wanjuan Wang
1
4
,
Xu Liu
1
2
3
,
Tao Li
1
4
,
Zhihong Yang
3
,
Xia Ding
4
,
Felix Aikhionbare
2
,
Xinjiao Gao
1
,
Zhikai Wang
1
2
,
Xing Liu
1
2
,
Xuebiao Yao
1
Affiliations
1
MOE Key Laboratory for Cellular Dynamics, University of Science & Technology of China School of Life Sciences, Hefei 230027, China.
2
Keck Center for Organoids Plasticity and Department of Surgery, Morehouse School of Medicine, Atlanta, GA 30310, USA.
3
Anhui Key Laboratory for Cellular Dynamics & Chemical Biology, CAS Center of Excellence in Molecular Cell Sciences, Hefei 230027, China.
4
Department of Gastroenterology, Beijing University of Chinese Medicine, Beijing 100081, China.
PMID:
35090026
PMCID:
PMC9122654
DOI:
10.1093/jmcb/mjac007
No abstract available
MeSH terms
Angiotensin-Converting Enzyme 2
COVID-19*
Humans
Organoids
SARS-CoV-2
Virus Internalization
Substances
Angiotensin-Converting Enzyme 2