Eye anomalies in children born through ART

Rom J Ophthalmol. 2021 Oct-Dec;65(4):310-314. doi: 10.22336/rjo.2021.65.

Abstract

Due to the increasing rate of couples suffering from infertility, recently, the use of assisted reproductive technology (ART) has increased by 5%-10% per year. Some ART pregnancies are at risk of obstetric and neonatal complications, but it is unknown whether the procedures used or the etiology of infertility influences this risk. Multiple ART pregnancies are responsible for the increased rate of prematurity and its associated complications. Also, it has been demonstrated that ART pregnancies have a higher risk of congenital anomalies. The rate of ART-associated ocular abnormalities is incompletely known due to a small number of studies conducted regarding this pathology. In this paper, we presented a review of literature on ocular anomalies associated with ART in order to raise awareness of the need to implement ophthalmological screening in children from pregnancies obtained by ART. Abbreviations: ART = assisted reproductive techniques, IVF = in vitro fertilization, ICSI = intracytoplasmic sperm injection, LBW = low birth weight, ROP = retinopathy of prematurity.

Keywords: assisted reproductive techniques; eye anomalies; ophthalmological screening.

Publication types

  • Review

MeSH terms

  • Child
  • Female
  • Fertilization in Vitro
  • Humans
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Outcome*
  • Pregnancy, Multiple
  • Reproductive Techniques, Assisted*
  • Sperm Injections, Intracytoplasmic